Lab 257 is located on Plum Island off the eastern edge of Long Island. Established after the second World War (in part by an Operation Paperclip Nazi recruit) it has been involved in developing biological weaponry for decades. It began as an Army institution but is currently under the aegis of homeland security, having spent most of the last few decades under the Department of Agriculture, ostensibly as an investigator of animal diseases. The book tells of the various known, or suspected, leaks of evil substances that have occurred during its existence, the personnel involved in the management and running of the institution, the effect of privatization, relations with its Long Island neighbors and its potential culpability in various epidemics, including Lyme disease and West Nile Virus. Perhaps the most significant message here is that Plum Island and its labs are on the map to terrorists and are vulnerable to disruption. Should bad guys get their hands on materials held at Lab 257, the results could be disastrous, on a level with a nuclear attack. It is a well-researched book, with a host of interesting and alarming pieces of information.